Prokaryotic genomes of endosymbionts and parasites are examples of naturally evolved minimal cells, the study of which can shed light on life in its minimum form. Their diverse biology, their lack of a large set of orthologous genes and the existence of essential linage (and environmentally) specific genes all illustrate the diversity of genes building up naturally evolved minimal cells. This conclusion is reinforced by the fact that sometimes the same essential function is performed by genes from different evolutionary origins. (...) Nevertheless, all cells perform a set of life‐essential functions however different their cell machinery and environment in which they thrive. An upcoming challenge for biologists will be to discern, by studying differences and similarities in current biodiversity, how cells with reduced genomes have adapted while retaining all basic life‐supporting functions. (shrink)

Desde su nacimiento bajo la pluma de Arthur Conan Doyle, Sherlock Holmes ha sabido adaptarse a los nuevos tiempos; en la actualidad, existen series, películas, videojuegos, e incluso, experiencias virtuales basadas en las obras originales. Este artículo lleva a cabo un análisis evolutivo del concepto de interactividad -desde la previrtualidad literaria de Gil González (2020) hasta la cultura participativa de Jenkins et al. (2015), el lectoespectador de Mora (2012), el interactor de Murray (1997) o el operador de Gubern (1996)-, en (...) los medios de la literatura, el cine y el videojuego en el corpus holmesiano. Para ello, se realiza una amplia revisión bibliográfica desde la perspectiva de la literatura comparada y los estudios intermediales, así como un abordaje crítico-analítico de algunas obras del universo del popular detective especialmente significativas en diferentes medios. (shrink)

¿En qué consistiría una filosofía de la universidad? ¿Cómo esbozar el modo en que ésta puede proceder? ¿Qué puede decir hoy la filosofía para quienes trabajan en esta institución? Para responder estas preguntas se propone revisar algunos de los textos en los que el pensador de origen argelino habla de manera directa sobre la universidad: Las pupilas de la Universidad, La Universidad sin condición y Cátedra vacante: censura, maestría y magistralidad. Los tres textos fueron escritos para ser leídos en público (...) como lecciones inaugurales o conferencias. La tesis de este artículo es que una filosofía de la universidad debe asumir que esta institución es el lugar en el que todo debe ser cuestionado y debe reflexionar críticamente sobre las metáforas que se usan para referirse a su razón de ser, su esencia y fundamento. Para desarrollar la idea central el artículo se organiza en cuatro partes: primero, se revisa el modo de proceder y las preocupaciones generales, a partir de la relación que se puede establecer con elementos de dos textos de Martin Heidegger; segundo, se examina las metáforas sobre la visión y la luz; tercero, se reflexionará sobre la destinación y razón de ser de la universidad; por último, se tratará la pregunta ¿quiénes somos nosotros en esta corporación de profesores y alumnos? (shrink)

The current COVID-19 crisis may have an impact on the mental health of professionals working on the frontline, especially healthcare workers due to the increase of occupational psychosocial risks, such as emotional exhaustion and secondary traumatic stress. This study explored job demands and resources during the COVID-19 crisis in predicting emotional exhaustion and STS among health professionals. The present study is a descriptive and correlational cross-sectional design, conducted in different hospitals and health centers in Spain. The sample consisted of 221 (...) health professionals with direct involvement in treating COVID-19. An online survey was created and distributed nationwide from March 20 to April 15 which assessed: sociodemographic and occupational data, fear of contagion, contact with death/suffering, lack of material and human protection resources, challenge, emotional exhaustion, and STS. Descriptive findings show high levels of workload, contact with death/suffering, lack of MHPR and challenge, and are moderately high for fear of contagion, emotional exhaustion, and STS. We found an indirect significant effect of lack of MHPR on predicting emotional exhaustion through the workload and on STS through fear of contagion, contact with death/suffering, and workload. To conclude, this study examines the immediate consequences of the crisis on health professionals' well-being in Spain, emphasizing the job demands related to COVID-19 that health professionals are facing, and the resources available in these health contexts. These findings may boost follow-up of this crisis among health professionals to prevent them from long-term consequences. (shrink)

Nowadays, the quality standards of higher education institutions pay special attention to the performance and evaluation of the students. Then, having a complete academic record of each student, such as number of attempts, average grade and so on, plays a key role. In this context, the existence of missing data, which can happen for different reasons, leads to affect adversely interesting future analysis. Therefore, the use of imputation techniques is presented as a helpful tool to estimate the value of missing (...) data. This work deals with the academic records of engineering students, in which imputation techniques are applied. More specifically, it is assessed and compared to the performance of the multivariate imputation by chained equations methodology, the adaptive assignation algorithm based on multivariate adaptive regression splines and a hybridization based on self-organisation maps with Mahalanobis distances and AAA algorithm. The results show that proposed methods obtain successfully results regardless the number of missing values, in general terms. (shrink)

Batteries are a fundamental storage component due to its various applications in mobility, renewable energies and consumer electronics among others. Regardless of the battery typology, one key variable from a user’s perspective is the remaining energy in the battery. It is usually presented as the percentage of remaining energy compared to the total energy that can be stored and is labeled State Of Charge (SOC). This work addresses the development of a hybrid model based on a Lithium Iron Phosphate (LiFePO4) (...) power cell, due to its broad implementation. The proposed model calculates the SOC, by means of voltage and electric current as inputs and the latter as the output. Therefore, four models based on k-Means, Agglomerative Clustering, Gaussian Mixture and Spectral Clustering techniques have been tested in order to obtain an optimal solution. (shrink)

This article analyzes process management and its financial impact on industrial companies in Ecuador and Latin America. Through a literature review and case analysis, process management practices, their benefits and challenges, and how these practices influence the financial results of companies are explored. It highlights the key aspects that contribute to improving operational efficiency and profitability, providing recommendations for successfully implementing process management in the industrial sector.

This paper aims to enhance security in IoT device networks through a visual tool that utilizes three projection techniques, including Beta Hebbian Learning (BHL), t-distributed Stochastic Neighbor Embedding (t-SNE) and ISOMAP, in order to facilitate the identification of network attacks by human experts. This work research begins with the creation of a testing environment with IoT devices and web clients, simulating attacks over Message Queuing Telemetry Transport (MQTT) for recording all relevant traffic information. The unsupervised algorithms chosen provide a set (...) of projections that enable human experts to visually identify most attacks in real-time, making it a powerful tool that can be implemented in IoT environments easily. (shrink)

After the global economic collapse triggered by the Great Recession, there has been an increased interest in the potential psychological implications of periods of economic decline. Recent evidence suggests that negative personal experiences linked to the economic crisis may lead to diminished generalized trust (i.e., the belief that most of the people of the society are honest and can be trusted). Adding to the growing literature on the psychological consequences of the economic crisis, we propose that the perceived personal impact (...) of the economic crisis not only would undermine generalized trust but also may lead to increased interpersonal trust (i.e., directed to specific and close people) and depersonalized in-group trust (i.e., directed to individuals who, while strangers, belong to the same group [e.g., social class]). Across three studies (N = 1379), we tested these central hypotheses and ascertained whether the perceived personal impact of the crisis would predict these types of trust (assessed using questionnaire and behavioral measures) independent of individuals’ socioeconomic status. Non-experimental data from Study 1 revealed that a higher perceived personal impact of the crisis is related to lower levels of generalized trust and higher levels of interpersonal trust. These effects were independent of participants’ socioeconomic status. Non-experimental data from Study 2 replicated the findings obtained in Study 1 and also showed a positive association between the perceived personal impact of the crisis and depersonalized in-group trust. This pattern of results emerged even after controlling for socioeconomic status, gender, age, political orientation, religiosity, and unemployment status. In Study 3, using an experimental design, we found that the salience of a possible economic downturn led to decreased generalized trust and increased interpersonal and depersonalized in-group trust—independently of socioeconomic status—compared with the control condition. These results challenge the conventional wisdom that economic crises invariably undermine trust in others. The implications of the present research as well as future research directions are discussed. (shrink)

Background: The acquisition of experience is a major concern for nurses in intensive care units. Although the emotional component of the clinical practice of these nurses has been widely studied, greater examination is required to determine how this component influences their learning and practical experience. Objective: To discover the relationships between emotion, memory and learning and the impacts on nursing clinical practice. Research design: This is a qualitative phenomenological study. The data were collected from open, in-depth interviews. A total of (...) 22 intensive care unit nurses participated in this research between January 2012 and December 2014. Ethical considerations: The School of Nursing Ethics Committee approved the study, which complied with ethical principles and required informed consent. Findings: We found a clear relationship between emotion, memory and the acquisition of experience. This relationship grouped three dimensions: (1) satisfaction, to relieve the patient’s pain or discomfort, give confidence and a sense of security to the patient, enable the presence of family members into the intensive care unit and provide family members with a realistic view of the patient’s situation; (2) error experience, which nurses feel when a patient dies, when they fail to accompany a patient in his or her decision to abandon the struggle to live or when they fail to lend support to the patient’s family; and (3) the feel bad–feel good paradox, which occurs when a mistake in the patient’s care or handling of his or her family is repaired. Conclusion: Emotion is a capacity that impacts on nurses’ experience and influences improvements in clinical practice. Recalling stories of satisfaction helps to reinforce good practice, while recalling stories of errors helps to identify difficulties in the profession and recognise new forms of action. The articulation of emotional competencies may support the development of nursing ethics in the intensive care unit to protect and defend their patients and improve their relationships with families in order to maximise the potential for patient care. (shrink)

RESUMEN El presente trabajo está dirigido a exponer elementos inherentes al modelo de superación profesional del tecnólogo de la salud en laboratorio clínico desde la integración ciencias básicas biomédicas-laboratorio. Entre los métodos teóricos empleados, el analítico-sintético permitió la determinación de los fundamentos epistemológicos y praxiológicos del proceso de superación, el inductivo-deductivo posibilitó la determinación de las categorías que surgen en el proceso investigativo, el sistémico estructural funcional para fundamentar el carácter de sistema del modelo y la modelación con la finalidad (...) de construirlo. Se concluye que se establecen como subsistemas del modelo, la proyección profesional de las ciencias básicas biomédicas, la contextualización profesional de la integración ciencias básicas biomédicas-laboratorio y la valoración contextual de la integración en el proceso de superación, lo que explica el proceso de superación del tecnólogo de la salud en laboratorio clínico. ABSTRACT This paper aims at setting out elements inherent to the health technologist in clinical laboratory’s professional training model from the integration of basic biomedical-laboratory sciences. Among the theoretical methods used, analysis-synthesis allowed establishing the epistemological and praxeological basis of the training process; the inductive-deductive method made it possible to determine the categories that result from the research process and the systemic-structural-functional method was used to support the system-like nature of the model and modelling with the end of building it. In conclusion, subsystems of the model are established: basic biomedical sciences professionals’ aims, professional conceptualization of the integration of basic biomedical-laboratory sciences and the contextual assessment of integration in the training process, which expounds the training process of the health technologist in clinical laboratory. (shrink)

Dans sa thèse de médecine de 1943 sur le normal et le pathologique, Georges Canguilhem se sert largement des idées de Kurt Goldstein lorsqu’il définit la normalité comme la capacité de l’organisme à créer de nouvelles normes de vie dans un débat polarisé avec son milieu. Pourtant, il déclara ensuite que les conceptions de Goldstein avaient constitué pour lui un « encouragement et non une inspiration ». Les archives personnelles de Canguilhem nous permettent effectivement de considérer le rapport de Canguilhem (...) à Goldstein comme une convergence plutôt que comme une influence mais surtout, l’usage que Canguilhem fait de Goldstein nous permet de mieux saisir la portée de ses propres idées. Nous interrogeons dans une première partie la conception holiste de l’organisme de Goldstein, dans ses rapports à la gestalt-théorie et à Kant, conception qui se réfère au processus d’actualisation de l’essence de l’organisme dans son rapport avec le milieu. Ceci nous permet d’appréhender l’usage que fait Canguilhem de certains concepts et idées de Goldstein pour élaborer son propre concept de normativité vitale. Dans une deuxième partie, nous nous proposons de comprendre la manière dont Canguilhem pose le problème du rapport de la connaissance à la normativité vitale à partir de sa lecture des textes du neurologue allemand. (shrink)

Vers la fin des années 1750, une Académie de Mathématiques fut créée au sein de l’Académie Militaire de la Garde du Corps à Madrid, dirigée par Pedro Padilla (1724-1807?) jusqu’à sa fermeture en 1760. En 1753, Padilla commença à publier son Cours Militaire de Mathématiques (1753 -1756) pour l’usage de cette Académie. Le besoin de textes mathématiques en espagnol dans le domaine militaire a conduit à la création en 1757 de la Société Royale Militaire de Mathématiques à Madrid sous la (...) direction de Pedro de Lucuce (1692-1779), lui aussi directeur de l’Académie Militaire de Mathématiques de Barcelone depuis 1738. Les membres de la Société ont été chargés de l’élaboration d’un cours complet dans lequel les mathématiques étaient considérées comme essentielles à la formation militaire des officiers artilleurs et des ingénieurs militaires. La Société, supprimée en 1760, a réussi à réunir une excellente bibliothèque scientifique et technique servant à son tour à fournir des futures bibliothèques militaires. Le but de cette contribution est d’explorer et de comparer la manière dont l’étude des mathématiques a été abordée dans ces deux cas. Toward the end of 1750, an Academy of Mathematics was established within the Military Academy of Royal Guards of Madrid that was managed by Pedro Padilla (1724-1807?) until it closed in 1760. In 1753, Padilla authored and published his Military Course of Mathematics (1753-1756) for the specific use by this Academy. The further need for mathematical texts in Spanish for military training coursework led to the founding of the Royal Military Society of Mathematics of Madrid in 1757 under the direction of Pedro de Lucuce (1692-1779), the headmaster of the Barcelona Military Academy of Mathematics since 1738. The members of this Society were entrusted with producing a comprehensive course program in which mathematics was considered and presented as essential to training of military engineers and gunners. The Society of Mathematics was dissolved in 1760 but had succeeded in building an extensive scientific and technical book depository that later served as a valuable resource supplying other military libraries. The aim of this contribution is to explore and compare how the study of mathematics was approached in these two cases. (shrink)

En este trabajo realizo un examen crítico del reciente libro de Silvana Gabriela Di Camillo sobre la crítica de Aristóteles a la teoría platónica de las Ideas. El libro de Di Camillo es un trabajo muy serio cuya lectura recomiendo ampliamente. Sin embargo, considero que cuatro de las principales tesis que la autora defiende tienen varias dificultades y mi objetivo aquí es presentar argumentos detallados en contra de ellas: la interpretación de la distinción entre argumentos más y menos rigurosos del (...) tratado Sobre las Ideas; la tesis de que la separación es el blanco esencial de las críticas aristotélicas a las Ideas; la interpretación de las opciones que Platón tiene para responder al argumento del tercer hombre, y la tesis de que la separación de las Ideas debe entenderse como homonimia. In this paper I examine Silvana Gabriela Di Camillo's recent book on Aristotle's criticisms of Plato's theory of Ideas. Di Camillo's book is a very serious work that I highly recommend. Nevertheless, I consider that four of the main theses that the author defends face several difficulties and my aim here is to offer detailed arguments against them: the interpretation of the distinction between more and less accurate arguments of the treatise On Ideas; the thesis that separation is the essential target of Aristotle's criticisms against Plato's Ideas; the interpretation of the options available to Plato to reply to the third man argument; and the thesis that the separation of Ideas should be understood as homonymy. (shrink)

On 20 December 1973, an attack by ETA put an end to the lives of Franco's head of government, his chauffeur and his bodyguard. This had important consequences for both the dictatorship and the terrorist group. Based on the existing sources, historians have developed a fairly credible account of the events. Nevertheless, the fact that ETA had managed to assassinate such a prominent politician, combined with some loose ends in the police investigation and the absence of a sentence gave rise (...) to all kinds of speculation. Furthermore, the case of Carrero Blanco has inspired narratives of uneven quality. In this paper we examine the interrelationship between history, conspiracy theories and fiction surrounding the attack. (shrink)

Colombia was one of the first countries to decriminalise euthanasia. However, what is known in the international academic literature about the country's regulations is scarce and outdated. Such lack of information on the situation in Latin America is even more evident in the case of Peru, where the Lima Superior Court of Justice set a precedent by allowing a person to have access to euthanasia in 2021. Ecuador, which has just decriminalised euthanasia for all its citizens in February 2024, risks (...) being similarly absent from the international dialogue. This article summarises for the first time all the regulations in force regarding euthanasia in Latin America, through a study of primary sources in Spanish, and analyses some of the convergences between these three neighbouring countries. (shrink)

By considering the position of education as a pharmakon, highlighting its potential positive and negative effects on societies by its technical unfolding, the article proposes to explore the political and pedagogical role that public and collective performances can have within the public sphere as political devices for promoting and enacting radical democracy. To this end, it analyzes a contemporary collaborative artistic practice, the performance ‘Un Violador en Tu Camino’ (‘A rapist in your path’) by the feminist collective LASTESIS from Chile, (...) through two main philosophical perspectives: Bernard Stiegler (1952 – 2020), and his approach to technology, to art, and education in human societies; and Oliver Marchart, coming from his conceptualization of art and activism through the notion of conflictual aesthetics. (shrink)

Mechanistic frameworks of investigation and explanation dominate the cognitive, neural, and psychological sciences. In this dissertation, I argue that mechanistic frameworks cannot, in principle, explain some kinds of cognition. In its place, I argue that complexity science has methods and theories more appropriate for investigating and explaining some cognitive phenomena. -/- I begin with an examination of the term 'cognition.' I defend the idea that "cognition" has been a moving target of investigation in the relevant sciences. As such it is (...) not historically true that there has been a thoroughly entrenched and agreed upon conception of "cognition." Next, I take up mechanistic frameworks. Although 'mechanism' is an umbrella term for a set of loosely related characteristics, there are common features: linearity, localization, and component dominance. I then describe complexity science, with emphasis on its utilization of dynamical systems modeling. Next, I discuss two phenomena that typically fall under the purview of complexity science: nonlinearity and interaction dominance. -/- A complexity science framework guided by the theory of self-organized criticality and utilizing the methods of dynamical systems modeling can surmount a number of challenges that face mechanistic frameworks when investigating some kinds of cognition. The first challenge is epistemic and concerns the inadequacy of mechanistic frameworks to facilitate the comprehensibility of massive amounts of data across various scales and areas of inquiry. I argue that complexity science is more appropriate for making big data comprehensible when investigating cognition, particularly across disciplines. I demonstrate this via an approach called nested dynamical modeling (NDM). NDM can facilitate comprehensibility of large amounts of data obtained from various scales of investigation by eliminating irrelevant degrees of freedom of that system as relates to the target of investigation. -/- The second shortcoming concerns ontological blind spots within mechanistic frameworks. Cognitive phenomena like extended cognition often fail to meet most, if not all, of the criteria assumed by many mechanistic approaches, especially component dominance. I argue that research guided by the notion of interaction dominance allows for extended cognition to be a real, empirically supported phenomenon within complex systems frameworks. In this chapter I discuss some of my experimental work on extended cognitive systems. -/- The search for mechanisms can be a reasonable starting position when attempting to explain natural phenomena in the life sciences. However, too strict of an adherence to theoretical and methodological commitments such as linearity, localization, and component dominance can result in intractable epistemic challenges and ontological blind spots. Complexity science has theories and methods to overcome such challenges in the investigation of cognition. (shrink)

O artigo defende a validade dos argumentos transcendentais. Hilary Putnam fez uso deste tipo de argumento para fixar uma condição metafísica para a semântica. Seu raciocínio segue o estilo de inferência desenvolvido por Kant, na refutação do ceticismo fenomenista e idealista. Segue-se da argumentação de Putnam a necessidade metafísica do princípio externalista em semântica. Com isso, desarmam-se as tentativas de fixar condicionamentos exclusivamente intersimbólicos para a constituição do significado.

A Teoria da Ação Comunicativa resulta de uma investigação acerca dos fundamentos da racionalidade prática, desenvolvida por Habermas nos últimos 30 anos. Neste artigo, serão analisados os aspectos básicos desta teoria, com ênfase nos pontos que a referenciam como modelo explanatório das nossas práticas comunicativas. Pretendo discutir prioritariamente a tese segundo a qual nossas condutas linguísticas são conduzidas por compromissos pragmático-universais. A aceitação desta tese depende da possibilidade de explicitação dos compromissos determinantes das ações comunicativas válidas. Com base neste exame, (...) vou propor a discussão de alguns pontos que me parecem mais frágeis na teoria de Habermas. Finalmente, pretendo contrastar este programa de reconstrução racional da comunicação com modelos teóricos pragmáticos não alinhados a priori com premissas racionalistas. Concluirei, a partir daí, que o argumento central de Habermas se fragiliza quando aplicado ás condições multilaterais e difusas nas quais os usos da linguagem efetivamente ocorrem. (shrink)

recover that lost impetus, that onward movement of creativeness, which is of its very essence of Life. Full self-realization can only be opened up to it, ...